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Energy Balance Core

Director:

James Levine, M.D., Ph.D. (Professor of Medicine, Endocrinology)

Key Personnel:

Bruce Johnson, Ph.D. (Co-investigator; Assoc. Prof. of Medicine, Cardiovascular)

Donald Hensrud, M.D. (Co-investigator; Assoc. Prof. of Nutrition and Preventive Medicine)

Description:

The Energy Balance core provides equipment and services to develop and examine energy balance from population to cell. The Energy Balance Core has facilities and equipment located at the Saint Marys and Methodist-Charlton Clinical Research Units.

James Levine, MD, Ph.D. is the director of the Energy Balance Core. His research area focuses on non-exercise activity thermogenesis (NEAT), the way the body burns calories through all the activities of daily living. His research studies NEAT in people, populations, and within the brains of humans and animals.

Bruce Johnson, Ph.D. is a co-investigator of this Translational Technology Core. His research interests center around heart and lung interactions under various conditions (e.g., hypoxia, high altitude, exercise) and in various populations (e.g., heart failure, health, lung disease, aging).

Donald Hensrud, M.D. is a co-investigator of this Translational Technology core. His research focuses on the following areas: obesity, nutrition and disease prevention, physical activity and health promotion, and clinical preventive medicine.

Services/Equipment:

Exercise:

  • Consultation for exercise protocol development available.
  • Facilities available at Saint Marys CRU only
  • Treadmill or cycle ergometer, 12-lead EKG, gas exchange with mass spectrometry, (standard VO2) facility with technical support provided for gas exchange/EKG.
  • Training provided for non-invasive cardiac output rebreathing measurements.
  • Isometric knee extension and isometric handgrip equipment (available at Methodist-Charlton CRU).

Indirect Calorimetry-Energy Expenditure Assessment

  • Energy expenditure measurement technical support provided at the CRU with possibility of training for investigative team.
  • Equipment currently is DeltaTrac Metabolic Monitor for Canopy measurement and face mask interface at rest or level activity

Physical Activity Measurement System (PAMS)

  • This system uses multiple interlaced sensors to provide second-by-second assessments of all daily physical activities. PAMS is used by seven NIH PIs, as well as in China and in the International Activity Center in the West Indies.

Contact: